Thyroid Antibodies and the Mystery of Unexplained Weight Changes: What You Can Do

Blood tests

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Struggling with unexplained weight gain or loss?

If your weight is changing — despite eating well and keeping active — your thyroid health could be involved. Many UK adults report puzzling changes in weight and energy, which can be linked to thyroid antibodies.

What are thyroid antibodies, and how do they relate to weight?

Thyroid antibodies, including thyroglobulin and thyroid peroxidase antibody, are proteins made by your immune system that sometimes attack the thyroid gland. When this happens, your thyroid may underperform (hypothyroidism), often causing weight gain. Sometimes, it can become overactive (hyperthyroidism), leading to weight loss and palpitations. These immune system errors are common — affecting thousands across the UK.

Common thyroid antibody-related symptom clusters:

How can you check if thyroid antibodies are part of the story?

Using Mayfield Clinic's Home Blood Test Kit: Thyroid Antibodies (Thyroglobulin & TPO), you can check your antibody levels using a simple self-collected finger-prick blood sample with a TDL Tiny kit. Results are available within two days, giving you quick answers from a UK-based lab.

What next? Lifestyle tips while you await your results

Your next steps with Mayfield Clinic

Ready to get answers? Order your home thyroid antibodies test kit here, or book a convenient in-person test at Mayfield Clinic. Take control of your health and get peace of mind for your thyroid and your wellbeing.

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Frequently asked questions

Can thyroid antibodies cause both underactive and overactive thyroid?

Yes, both Hashimoto’s hypothyroidism and Graves’ disease (overactive thyroid) are linked to raised thyroid antibodies, which you can detect at home with Mayfield’s kit.

Can I improve thyroid antibody levels through lifestyle changes?

Lifestyle plays a role: managing stress, maintaining a healthy weight, and a balanced diet support overall thyroid health. However, underlying autoimmune processes may still require medical follow-up.

What happens if my test result is abnormal?

If your test shows raised thyroid antibodies, consult with your GP. You may be referred for further thyroid function tests or specialist advice.

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